Cell attachment onto Bioglass-derived glass-ceramics can be imported through surface chemical treatment, such as silanisation using aminopopyl - triethoxysilane (APTS). One concern raised by this treatment is that the alkalinity of the silane could change the surface topography such that attached cells might eventually by negatively affected by the sharp ridges formed during silanisation. It is, therefore, necessary to find out an optimal treatment condition at which a monolayer of APTS forms on the glass-ceramic surface without leading to sharp features on the surface. In this work, Bioglass-derived glass-ceramics pellets were treated in an APTS solution at 80 C for 1,2,3 & 4 h, immediately followed by microstructural & compositional analysis.
