The formation and the properties of the oxide compounds are determined by intrinsic factors (depending on the reactants) and extrinsic ones (reaction conditions). The formation reactions are defined by a series of thermodynamic functions. In this paper, the correlation between the Gibbs free energy of formation are highlighted, along with the reaction of energy and the basicity of reacting oxides, respectively, evaluated through the basicity percentage, pB, in % in the CaO-SiO2 system. At the same time, for a series of properties (interaction with water, hydration degree, mechanical resistance to compression, shrinkage) of some mineralogical constituents of the Portland cement clinker highlights their interdependence with basicity.