Preparation Of Compositionally Graded Spherical Particles Of Hydroxyapatite/Acesulfame-K By Spray Drying

Spray drying is a process in which an aqueous solution containing dissolved materials is sprayed into a high-temperature furnace in order that the materials undergo instant drying to form powder. The powder thus formed consists of filled or hollow spherical particles. Internal and external compositionally graded spherical particles prepared by the spray-drying method using a solution that contained two compounds with different solubilities were considered. This study investigated the preparation of compositionally graded spherical particles by spray drying a solution containing the low-solubility material by hydroxyapatite, and the high-solubility material acesulfame-K.