Peripheral nerve injuries are frequent conditions that currently have very few treatment alternatives. This study aimed to incorporate aligned bioactive glass microfibers in nanofibrous poly e-caprolactone (PLC) membranes to develop a new biocomposite that is potentially able to facilitate nerve growth and increase the polymer matrix's biological and mechanical properties. For the manufacture of this novel tubular nerve guide, electrospinning of PLC was performed on the surface of bioactive glass fibres, resulting in a two-layer microcomposite. The mechanical strength, bioactivity, wettability, degradation, and permeability of this new material were characterized. The preliminary results indicate that the incorporation of the bioactive glass fibres into PCL led to the development of a highly bioactive biocomposite with significantly improved mechanical properties and wettability compared with the PCL matrix alone.
