Flouride is an important minerla for hard tissues in the body and appropriate flouride exposure and usage are beneficial to bone and tooth integrity. Flouride increases both bone density and bone massdue to stimulation of bone formation and it is used as a treatment for osteoperosis. Bioactive glasses have the cpacity to form an intimate bond with living bone tissue due to formation of a mixed hydrocarboxonate apatite layer (HCA) in vitro and in vivo. This makes flouride-containing bioactive glasses attractive materials. In order to design flouriode containing bioactive-glasses, we need to understand the role of flourine within the glass strucutre. A series of bioactive glasses with increasing flouride content was prepared by a melt-quench route.
